Showing posts with label Vitamin. Show all posts
Showing posts with label Vitamin. Show all posts

Thursday, April 30, 2015

Vitamin D, structure, food sources, deficiency, toxicity

Fat soluble vitamins:
They are dissolved in fat and reserved in the body almost a month. They are storage in the fatty tissues as well as the liver. Vitamin A, D, E, and K are the fat-soluble vitamin. They are absorbed in the GI tract with the help of fat. They are eliminated much more slowly than water-soluble vitamins.



Vitamin D:

Vitamin D is a fat-soluble vitamin essential for human. It plays a critical role in the use of calcium and phosphorus. It is important for immunity and cell growth. For strong bone and teeth development. It is much essential for a child.

Food sources of Vitamin D:

Vitamin D is made in our skin on the expose of sunlight. About 80-90% vitamin D can be synthesized under the skin by sunlight. Exposure of the hands, face, arms, and legs to sunlight two to three times a week for about one-fourth of the time it would take to develop a mild sunburn will cause the skin to produce enough vitamin D. Besides this some animals food sources can provide vitamin D includes:



  •     Eggs
  •     Fortified fat spreads
  •     Fortified breakfast cereals
  •     Fatty fish such as herring
  •     Some powdered milk
  •     Oily fishes like Sardines and tuna salmon.
  •     Some mushrooms
  •     Cod liver oil

Structure of vitamin D:



Vitamin D deficiency:

Taking an inadequate amount of vitamin D may cause some diseases. Rickets and osteomalacia are the classical vitamin D deficiency diseases mostly in children.
Rickets, a disease characterized by a failure of bone tissue to properly mineralize, resulting in soft bones and skeletal deformities.
Osteomalacia causes muscle and bone weakness and osteoporosis causes loss of bone mass largely in adults.

RDA (Recommended dietary allowance):

Recommended dietary allowance for vitamin D appears as micrograms of cholecalciferol (vitaminD3).
           20mcg cholecalciferol = 800 international unit.(IU)
   For Infants,
                   0 - 12 months: 400 IU (10 micrograms (mcg) per day)
   For Children,
         1 - 8years: 600 IU (15 mcg/day)
   For adults,
        Adults over 70 years: 800 IU (20 mcg/day)
        Pregnancy and breast-feeding: 600 IU (15 mcg/day)

What happens if you take too much vitamin D?

Your body doesn't make too much vitamin D from sun exposure, but always remember to cover up or protect your skin if you are out in the sun for long periods or use sunscreen.
Taking too many vitamin D supplements over a long period of time can cause more calcium to be absorbed than can be excreted. The excess calcium can be deposited in and damage the kidneys. Excessive intake of vitamin D can also encourage calcium to be removed from bones, which can soften and weaken them. 

Risk factors of vitamin D:

It is essential to maintain vitamin D status for many people who consume vitamin D-fortified foods and, arguably, being exposed to some sunlight. Some groups need extra vitamin D in the form of supplements or fortified foods.
Breastfed infants:
Human milk provides only <25 IU/L to 78 IU/L of vitamin D. So All breastfed infants should have 400 IU per day. It must be recall that a mother should have a good vitamin D status, otherwise infants may suffer from some deficiency like rickets.
Older adults:
Vitamin D efficiency is decreased with the increase of age. For older people, the skin cannot synthesize vitamin D as efficiently, they are likely to spend more time indoors, and they may have inadequate intakes of the vitamin.
People with Dark skin:
Those who have darkly pigmented skin cannot synthesize vitamin D than the light pigmented skin. So they have to take extra vitamin D in their diet.
Covered or protective skin:
Those who wear or covered all of their skin with clothes and use sunscreen, they may block the synthesis of vitamin D from sunlight.
People with inflammatory bowel disease and other conditions causing fat malabsorption:
Fat malabsorption is associated with a variety of medical conditions, including some forms of liver disease, cystic fibrosis, celiac disease, and Crohn's disease, as well as ulcerative colitis when the terminal ileum is inflamed. Fat malabsorption symptoms, inflammatory bowel disease, and obesity can prevent vitamin D absorption.








Tuesday, April 7, 2015

Why Mammals can not Synthesize vitamin C

Water soluble vitamins:
They are soluble in water and soon get expelled in the urine after ingested. They do not stored in the body and so needed daily. They rapidly absorbed in the body. Vitamin C and vitamin B complex are water soluble vitamins.



Vitamin C:

Vitamin C also known as ascorbic acid is an essential vitamin because the body needs it to remain proper working condition. It participates in the collagen synthesis. Collagen is a connective tissue that holds muscles, bones, and another tissue together. It is an antioxidant also aid wound healing, bone and tooth formation and improves in an immune system. It plays an important role in iron absorption and utilization.




Food sources:

Vitamin C is very common in plant especially in the citrus fruits. Leafy green vegetables and colorful fruits  contain the large amount of vitamin C. Oranges, Kiwi fruits, grapes, lemons, sweet red pepper etc. have plenty of vitamin C.




RDA (Recommended dietary allowance):
Recommended dietary allowance for vitamin C is 90mg/day for adult males and 75mg/day for adult females. Those who smoke cigarettes the RDA  increases by 35mg/day to reduce the oxidative effect of nicotine.

Structure of vitaminC:




Vitamin C deficiency:
Severe deficiency of vitamin C may result in the disease known as scurvy, causing the loss of collagen strength  through the body. Loss of collagen results in loose teeth, bleeding and swollen gums and improve wound healing.It is more common in children and alcohol consuming people.


Causes of Vitamin C deficiency:
This is due to lack of the vitamin in the diet. The risk factors includes-
  • People who take alcohol.
  • Babies who take only cow’s milk during childhood.
  • Elderly individuals who take a tea- toast diet.
  • Pregnant and lactating women.
  • People with Type-1 diabetes.
  • People with AIDS and cancers.
Mammals can not Synthesize vitamin C:






The human body lack the ability to synthesize vitamin C, therefore, depend on dietary sources of vitamin C.They lack the enzyme called L-gluconolactone oxidase which convert L-gluconolactone to L-ascorbic acid.

Vitamin A structure, food sources,RDA,UL,deficiency,toxicity

Fat soluble vitamins:
They are dissolved in fat and reserved in the body for a whole day or almost a month. They are storage in the fatty tissues as well as in the liver. Vitamin A, D, E and K is a fat soluble vitamin. They are absorbed in the GI tract with the help of fat. They are eliminated much more slowly than water-soluble vitamins.



Vitamin A:
Vitamin A also called Retinol plays an important role in bone growth, tooth development, cell division, reproduction, gene expression and immune function. It plays role in the prevention of certain cancer as an antioxidant. Skin, eyes, mucous membranes depend on vitamin A to keep moist.


Structures of vitamin A:



Food sources:
Some dark orange and green vegetables contain an antioxidant called Beta- carotene which the body convert to vitamin A. Vitamin A sources also include carrots, pumpkin, winter squash, dark green leafy vegetables etc.

RDA (Recommended dietary allowance):
The Recommended dietary allowance for vitamin A is 900mcg/day for adult male and 700mcg/day for adult women.

Vitamin A deficiency:
Xeropthalmia most commonly occurs in the developing nations usually due to malnutrition. Night blindness and very dry, rough skin indicate a lack of vitamin A.Other possible vitamin A deficiency include that slower bone growth and tooth development as well as decrease resistance to infections.

UL (Upper intake level):
Tolerable upper intake level for an adult is 3000mcg RAE.

Symptoms of toxicity:
Symptoms of vitamin A toxicity include dry, itchy skin, headache, nausea, and loss of appetite. Vitamin A toxicity also causes severe birth defect and may increase the risk of hip fractures.



Monday, April 6, 2015

What are vitamins?

What are vitamins
Vitamins are organic substances required an organism very small amount to sustain life. Although it needed a little, it has a great importance for maintaining life. There are 13 vitamins needed in our body. They are essential because they cannot synthesize in the body (except vitamin D & K), therefore they must be obtained from food. Insufficient amount of vitamin may cause deficiency diseases.

Types of vitamin:
Vitamins are classified into two categories-Fat soluble vitamins and Water soluble vitamins.

Fat soluble vitamins:
They are dissolved in fat and reserved in the body almost a month. They are storage in the fatty tissues as well as the liver. Vitamin A, D, E and K are fat-soluble vitamin. They are absorbed in the GI tract with the help of fat. They are eliminated much more slowly than water-soluble vitamins.

Water soluble vitamins:
They are soluble in water and soon get expelled in the urine after ingested. They do not storage in the body and so needed daily. They rapidly absorbed in the body. Vitamin C and vitamin B complex are water soluble vitamins.